P518 Ulcerative colitis drug development success rates are higher than the industry average
نویسندگان
چکیده
منابع مشابه
Drug Therapy in Ulcerative Colitis
The two primary types of inflammatory bowel disease (IBD) are ulcerative colitis (CU) and Crohn's disease (CD). These two diseases have many similarities and sometimes are difficult to distinguish from each other. However, there are several differences. UC is an inflammatory destructive disease of the large intestine characterized by motility and secretion disorders. Inflammation usually occurs...
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Drug development in the United States has been characterized by: (1) high attrition and correspondingly low success rates of drug candidates passing through the development sys(2) a steady decline in new chemical entities (NCEs) entering clinical r e~ea rch ,~ -~ and (3) increasingly lengthy and more costly periods required for clinical and regulatory review.3 These characteristics have raised ...
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Patients 101 patients who were 18–80 years of age and had symptomatic (moderate or severe) grade 2 to 4 ulcerative colitis that extended >12 cm beyond the anal margin. Exclusion criteria were Crohn’s disease, idiopathic proctitis, noninflammatory bowel diseases, stool parasites, toxins, pathogens, use of steroids within the previous month, use of immunosuppressive agents in the previous 3 month...
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ژورنال
عنوان ژورنال: Journal of Crohn's and Colitis
سال: 2020
ISSN: 1873-9946,1876-4479
DOI: 10.1093/ecco-jcc/jjz203.646